Addressing standards of care in resource-limited settings.
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ABSTRACT:
SUBMITTER: Dawson L
PROVIDER: S-EPMC4169284 | biostudies-literature | 2014 Jan
REPOSITORIES: biostudies-literature
Publications
Addressing standards of care in resource-limited settings.
Dawson Liza L Klingman Karin L KL Marrazzo Jeanne J
Journal of acquired immune deficiency syndromes (1999) 20140101
: The choice between "best-known" standards of care (SOC) or "best available" standards as the control arm in a clinical trial is a fundamental dilemma in clinical research in resource-limited settings (RLS). When the health system is delivering less than an optimal level of care, using highest standard of care in a clinical trial may produce results that cannot be implemented or sustained locally. On the other hand, using interventions that are more feasible in the local setting may involve sub ...[more]
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