Decline in mean platelet volume in patients with patent foramen ovale undergoing percutaneous closure.

ABSTRACT:

Introduction

The presence of patent foramen ovale (PFO) is considered a possible cause for cryptogenic stroke. The mechanism underlying the ischaemic neurological events in the presence of PFO has not been firmly established. The purpose of this study was to compare: (1) the mean platelet volume levels in PFO patients with and without a cryptogenic stroke, and (2) pre- and post-procedural mean platelet volumes (MPV) in patients undergoing percutaneous PFO closure.

Methods

Sixteen PFO patients undergoing percutaneous closure to prevent recurrent ischaemic events and 15 asymptomatic patients with PFO were enrolled in the study. Mean platelet volume was compared between patients with and without a history of stroke. We also compared pre- and post-procedural MPV levels in patien

SUBMITTER: Duzel B 

PROVIDER: S-EPMC4170178 | biostudies-literature | 2014 Jul-Aug

REPOSITORIES: biostudies-literature