Susceptibility to Campylobacter infection is associated with the species composition of the human fecal microbiota.

ABSTRACT:

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The gut microbiota is essential for human health, but very little is known about how the composition of this ecosystem can influence and respond to bacterial infections. Here we address this by prospectively studying the gut microbiota composition before, during, and after natural Campylobacter infection in exposed poultry abattoir workers. The gut microbiota composition was analyzed with 16S amplicon sequencing of fecal samples from poultry abattoir workers during the peak season of Campylobacter infection in Sweden. The gut microbiota compositions were compared between individuals who became culture positive for Campylobacter and those who remained negative. Individuals who became Campylobacter positive had a significantly higher abundance of Bacteroides (P = 0.007) an

SUBMITTER: Dicksved J 

PROVIDER: S-EPMC4172070 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature