Ontology highlight
ABSTRACT:
SUBMITTER: St Pourcain B
PROVIDER: S-EPMC4175587 | biostudies-literature | 2014 Sep
REPOSITORIES: biostudies-literature
St Pourcain Beate B Cents Rolieke A M RA Whitehouse Andrew J O AJ Haworth Claire M A CM Davis Oliver S P OS O'Reilly Paul F PF Roulstone Susan S Wren Yvonne Y Ang Qi W QW Velders Fleur P FP Evans David M DM Kemp John P JP Warrington Nicole M NM Miller Laura L Timpson Nicholas J NJ Ring Susan M SM Verhulst Frank C FC Hofman Albert A Rivadeneira Fernando F Meaburn Emma L EL Price Thomas S TS Dale Philip S PS Pillas Demetris D Yliherva Anneli A Rodriguez Alina A Golding Jean J Jaddoe Vincent W V VW Jarvelin Marjo-Riitta MR Plomin Robert R Pennell Craig E CE Tiemeier Henning H Davey Smith George G
Nature communications 20140916
Twin studies suggest that expressive vocabulary at ~24 months is modestly heritable. However, the genes influencing this early linguistic phenotype are unknown. Here we conduct a genome-wide screen and follow-up study of expressive vocabulary in toddlers of European descent from up to four studies of the EArly Genetics and Lifecourse Epidemiology consortium, analysing an early (15-18 months, 'one-word stage', N(Total) = 8,889) and a later (24-30 months, 'two-word stage', N(Total)=10,819) phase o ...[more]