A novel restricted diffusion model of evoked dopamine.
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ABSTRACT:
SUBMITTER: Walters SH
PROVIDER: S-EPMC4176316 | biostudies-literature | 2014 Sep
REPOSITORIES: biostudies-literature
Publications
A novel restricted diffusion model of evoked dopamine.
Walters Seth H SH Taylor I Mitch IM Shu Zhan Z Michael Adrian C AC
ACS chemical neuroscience 20140710 9
In vivo fast-scan cyclic voltammetry provides high-fidelity recordings of electrically evoked dopamine release in the rat striatum. The evoked responses are suitable targets for numerical modeling because the frequency and duration of the stimulus are exactly known. Responses recorded in the dorsal and ventral striatum of the rat do not bear out the predictions of a numerical model that assumes the presence of a diffusion gap interposed between the recording electrode and nearby dopamine termina ...[more]
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