Anopheles gambiae densovirus (AgDNV) has negligible effects on adult survival and transcriptome of its mosquito host.
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ABSTRACT:
SUBMITTER: Ren X
PROVIDER: S-EPMC4179393 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Publications
Anopheles gambiae densovirus (AgDNV) has negligible effects on adult survival and transcriptome of its mosquito host.
Ren Xiaoxia X Hughes Grant L GL Niu Guodong G Suzuki Yasutsugu Y Rasgon Jason L JL
PeerJ 20140918
Mosquito densoviruses (DNVs) are candidate agents for paratransgenic control of malaria and other vector-borne diseases. Unlike other mosquito DNVs, the Anopheles gambiae DNV (AgDNV) is non-pathogenic to larval mosquitoes. However, the cost of infection upon adults and the molecular mechanisms underpinning infection in the mosquito host are unknown. Using life table analysis, we show that AgDNV infection has minimal effects on An. gambiae survival (no significant effect in 2 replicates and a sli ...[more]
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