Ontology highlight
ABSTRACT:
SUBMITTER: Shrestha SS
PROVIDER: S-EPMC4181537 | biostudies-literature | 2014 Mar
REPOSITORIES: biostudies-literature
Shrestha Stal Saurav SS Nelson Eric E EE Liow Jeih-San JS Gladding Robert R Lyoo Chul Hyoung CH Noble Pam L PL Morse Cheryl C Henter Ioline D ID Kruger Jeremy J Zhang Bo B Suomi Stephen J SJ Svenningsson Per P Pike Victor W VW Winslow James T JT Leibenluft Ellen E Pine Daniel S DS Innis Robert B RB
The American journal of psychiatry 20140301 3
<h4>Objective</h4>This study examined the long-term effects of fluoxetine administered to juvenile rhesus monkeys who, as young adults, were imaged with positron emission tomography for two serotonergic markers: serotonin transporter (SERT) and serotonin 1A (5-HT1A) receptor. An equal number of monkeys separated from their mothers at birth-an animal model of human childhood stress-were also studied.<h4>Method</h4>At birth, 32 male rhesus monkeys were randomly assigned to either maternal separati ...[more]