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First report of the ceftazidimase CTX-M-19 in South America.

ABSTRACT: We report the first detection of bla CTX-M-19 in South America, harboured in an Escherichia coli isolate obtained from a urine sample; such an isolate belonged to phylogenetic group A, ST603, and showed a ceftazidimase profile. bla CTX-M-19 was encoded in an approximately 100 kb IncI1/IncF conjugative plasmid, featuring pndAC and hok/sok addiction systems; the ?-lactamase gene was flanked upstream by three tandem-like transposons (IS26, IS10 and ISEcp1), inserted one inside the other, and downstream by IS903.

SUBMITTER: Garcia-Fulgueiras V

PROVIDER: S-EPMC4184694 | biostudies-literature | 2013 Dec

REPOSITORIES: biostudies-literature

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First report of the ceftazidimase CTX-M-19 in South America.

García-Fulgueiras V V Bado I I Cordeiro N F NF Algorta G G Vignoli R R

New microbes and new infections 20131222 3

We report the first detection of bla CTX-M-19 in South America, harboured in an Escherichia coli isolate obtained from a urine sample; such an isolate belonged to phylogenetic group A, ST603, and showed a ceftazidimase profile. bla CTX-M-19 was encoded in an approximately 100 kb IncI1/IncF conjugative plasmid, featuring pndAC and hok/sok addiction systems; the β-lactamase gene was flanked upstream by three tandem-like transposons (IS26, IS10 and ISEcp1), inserted one inside the other, and downst ...[more]

PMID: 25356329

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