Ontology highlight
ABSTRACT:
SUBMITTER: Ok CY
PROVIDER: S-EPMC4184926 | biostudies-literature | 2014 Oct
REPOSITORIES: biostudies-literature
Ok Chi Young CY Chen Jiayu J Xu-Monette Zijun Y ZY Tzankov Alexandar A Manyam Ganiraju C GC Li Ling L Visco Carlo C Montes-Moreno Santiago S Dybkær Karen K Chiu April A Orazi Attilio A Zu Youli Y Bhagat Govind G Richards Kristy L KL Hsi Eric D ED Choi William W L WW van Krieken J Han JH Huh Jooryung J Zhao Xiaoying X Ponzoni Maurilio M Ferreri Andrés J M AJ Bertoni Francesco F Farnen John P JP Møller Michael B MB Piris Miguel A MA Winter Jane N JN Medeiros L Jeffrey LJ Young Ken H KH
Clinical cancer research : an official journal of the American Association for Cancer Research 20140814 19
<h4>Purpose</h4>Activated signal transducer and activator of transcription 3 (STAT3) regulates tumor growth, invasion, cell proliferation, angiogenesis, immune response, and survival. Data regarding expression of phosphorylated (activated) STAT3 in diffuse large B-cell lymphoma (DLBCL) and the impact of phosphorylated STAT3 (pSTAT3) on prognosis are limited.<h4>Experimental design</h4>We evaluated expression of pSTAT3 in de novo DLBCL using immunohistochemistry, gene expression profiling (GEP), ...[more]