Ontology highlight
ABSTRACT:
SUBMITTER: Sive JI
PROVIDER: S-EPMC4188419 | biostudies-literature | 2012 May
REPOSITORIES: biostudies-literature
Sive Jonathan I JI Buck Georgina G Fielding Adele A Lazarus Hillard M HM Litzow Mark R MR Luger Selina S Marks David I DI McMillan Andrew A Moorman Anthony V AV Richards Susan M SM Rowe Jacob M JM Tallman Martin S MS Goldstone Anthony H AH
British journal of haematology 20120313 4
Although the incidence rate of acute lymphoblastic leukaemia (ALL) is slightly higher in older than in younger adults, response rates to induction chemotherapy and survival rates are poorer. The contribution of disease-related versus treatment-related factors remains unclear. We analysed 100 older patients (aged 55-65 years) treated on the UKALLXII/ECOG2993 trial compared with 1814 younger patients (aged 14-54 years). Baseline characteristics, induction chemotherapy course, infections, drug redu ...[more]