Ontology highlight
ABSTRACT:
SUBMITTER: D'Angelo R
PROVIDER: S-EPMC4190592 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
D'Angelo Rosalia R Scimone Concetta C Esposito Teresa T Esposito Teresa T Bruschetta Daniele D Rinaldi Carmela C Ruggeri Alessia A Sidoti Antonina A
Journal of medical case reports 20141006
<h4>Introduction</h4>Trimethylaminuria is a rare inherited disorder due to decreased metabolism of dietary-derived trimethylamine by flavin-containing monooxygenase 3. Several single nucleotide polymorphisms of the flavin-containing monooxygenase 3 gene have been described and result in an enzyme with decreased or abolished functional activity for trimethylamine N-oxygenation thus leading to trimethylaminuria.<h4>Case presentation</h4>Here we investigated an Italian family in which the proband w ...[more]