Ontology highlight
ABSTRACT:
SUBMITTER: Joo EE
PROVIDER: S-EPMC4190669 | biostudies-literature | 2014 Mar
REPOSITORIES: biostudies-literature
Joo E Emily EE Yamada Kenneth M KM
Nature communications 20140325
Although much is known about how individual cytoskeletal systems contribute to physiological processes such as cell migration and branching morphogenesis, little is known about how these different systems actively coordinate their functions after polymerization. Here we show that both fibroblasts and developing glands reciprocally coordinate levels of cellular contractility and microtubule acetylation. We find that this balance is achieved by interaction of the myosin phosphatase target subunit ...[more]