Ontology highlight
ABSTRACT:
SUBMITTER: Dahdah A
PROVIDER: S-EPMC4191002 | biostudies-literature | 2014 Oct
REPOSITORIES: biostudies-literature
Dahdah Albert A Gautier Gregory G Attout Tarik T Fiore Frédéric F Lebourdais Emeline E Msallam Rasha R Daëron Marc M Monteiro Renato C RC Benhamou Marc M Charles Nicolas N Davoust Jean J Blank Ulrich U Malissen Bernard B Launay Pierre P
The Journal of clinical investigation 20140902 10
Controlling the overwhelming inflammatory reaction associated with polymicrobial sepsis remains a prevalent clinical challenge with few treatment options. In septic peritonitis, blood neutrophils and monocytes are rapidly recruited into the peritoneal cavity to control infection, but the role of resident sentinel cells during the early phase of infection is less clear. In particular, the influence of mast cells on other tissue-resident cells remains poorly understood. Here, we developed a mouse ...[more]