Ontology highlight
ABSTRACT:
SUBMITTER: Nakamura T
PROVIDER: S-EPMC4191553 | biostudies-literature | 2014 Jul
REPOSITORIES: biostudies-literature
Nakamura Toshitaka T Matsumoto Toshio T Sugimoto Toshitsugu T Hosoi Takayuki T Miki Takami T Gorai Itsuo I Yoshikawa Hideki H Tanaka Yoshiya Y Tanaka Sakae S Sone Teruki T Nakano Tetsuo T Ito Masako M Matsui Shigeyuki S Yoneda Toshiyuki T Takami Hideo H Watanabe Ko K Osakabe Taisuke T Shiraki Masataka M Fukunaga Masao M
The Journal of clinical endocrinology and metabolism 20140319 7
<h4>Context</h4>Denosumab 60 mg sc injection every 6 months for 36 months was well tolerated and effective in reducing the incidence of vertebral, nonvertebral, and hip fracture in predominantly Caucasian postmenopausal women with osteoporosis.<h4>Objective</h4>The objective of this phase 3 fracture study was to examine the antifracture efficacy and safety of denosumab 60 mg in Japanese women and men with osteoporosis compared with placebo.<h4>Design and setting</h4>A randomized, double-blind, p ...[more]