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Draft Genome Sequence of the First Isolate of Extensively Drug-Resistant Mycobacterium tuberculosis in Ireland.

ABSTRACT: Extensive drug resistance is an emerging threat to the control of tuberculosis (TB) worldwide, even in countries with low TB incidence. We report the draft whole-genome sequence of the first reported extensively drug-resistant TB (XDR-TB) strain isolated in Ireland (a low-incidence setting) and describe a number of single-nucleotide variations that correlate with its XDR phenotype.

SUBMITTER: Roycroft E

PROVIDER: S-EPMC4192383 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature

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Draft Genome Sequence of the First Isolate of Extensively Drug-Resistant Mycobacterium tuberculosis in Ireland.

Roycroft Emma E Mac Aogáin Micheál M O'Toole Ronan F RF Fitzgibbon Margaret M Rogers Thomas R TR

Genome announcements 20141009 5

Extensive drug resistance is an emerging threat to the control of tuberculosis (TB) worldwide, even in countries with low TB incidence. We report the draft whole-genome sequence of the first reported extensively drug-resistant TB (XDR-TB) strain isolated in Ireland (a low-incidence setting) and describe a number of single-nucleotide variations that correlate with its XDR phenotype. ...[more]

PMID: 25301651

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