Ontology highlight
ABSTRACT:
SUBMITTER: Saisawang C
PROVIDER: S-EPMC4195677 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Saisawang Chonticha C Ketterman Albert J AJ
PloS one 20141013 10
Glutathione transferases (GST) are an ancient superfamily comprising a large number of paralogous proteins in a single organism. This multiplicity of GSTs has allowed the copies to diverge for neofunctionalization with proposed roles ranging from detoxication and oxidative stress response to involvement in signal transduction cascades. We performed a comparative genomic analysis using FlyBase annotations and Drosophila melanogaster GST sequences as templates to further annotate the GST orthologs ...[more]