Ontology highlight
ABSTRACT:
SUBMITTER: Liu R
PROVIDER: S-EPMC4203550 | biostudies-literature | 2014 Jul
REPOSITORIES: biostudies-literature
Liu Rui R Li Jingyi J Zhang Tao T Zou Linzhi L Chen Yi Y Wang Kui K Lei Yunlong Y Yuan Kefei K Li Yi Y Lan Jiang J Cheng Lin L Xie Na N Xiang Rong R Nice Edouard C EC Huang Canhua C Wei Yuquan Y
Autophagy 20140515 7
Glioblastoma is one of the most aggressive human cancers with poor prognosis, and therefore a critical need exists for novel therapeutic strategies for management of glioblastoma patients. Itraconazole, a traditional antifungal drug, has been identified as a novel potential anticancer agent due to its inhibitory effects on cell proliferation and tumor angiogenesis; however, the molecular mechanisms involved are still unclear. Here, we show that itraconazole inhibits the proliferation of glioblas ...[more]