Ontology highlight
ABSTRACT:
SUBMITTER: Sheridan RT
PROVIDER: S-EPMC4205123 | biostudies-literature | 2014 Jul
REPOSITORIES: biostudies-literature
Chembiochem : a European journal of chemical biology 20140606 10
Immunotherapy is a promising strategy for targeting tumors. One emerging approach is to harness the immune effector functions of natural antibodies to destroy tumor cells. Dinitrophenyl (DNP) and the galactose-α-1,3-galactose (αGal) epitope are two haptens that bind endogenous antibodies. One potential alternative is the deoxysugar L-rhamnose. We compared these candidates by using a biosensor assay to evaluate human sera for endogenous antibody concentration, antibody isotype distribution, and l ...[more]