Ontology highlight
ABSTRACT:
SUBMITTER: Pachulec E
PROVIDER: S-EPMC4207684 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Pachulec Emilia E Siewering Katja K Bender Tobias T Heller Eva-Maria EM Salgado-Pabon Wilmara W Schmoller Shelly K SK Woodhams Katelynn L KL Dillard Joseph P JP van der Does Chris C
PloS one 20141023 10
Neisseria gonorrhoeae is an obligate human pathogen that is responsible for the sexually-transmitted disease gonorrhea. N. gonorrhoeae encodes a T4SS within the Gonococcal Genetic Island (GGI), which secretes ssDNA directly into the external milieu. Type IV secretion systems (T4SSs) play a role in horizontal gene transfer and delivery of effector molecules into target cells. We demonstrate that GGI-like T4SSs are present in other β-proteobacteria, as well as in α- and γ-proteobacteria. Sequence ...[more]