Ontology highlight
ABSTRACT:
SUBMITTER: te Velthuis AJ
PROVIDER: S-EPMC4207942 | biostudies-literature | 2014 Nov
REPOSITORIES: biostudies-literature
Cellular and molecular life sciences : CMLS 20140801 22
Eukaryotes and bacteria can be infected with a wide variety of RNA viruses. On average, these pathogens share little sequence similarity and use different replication and transcription strategies. Nevertheless, the members of nearly all RNA virus families depend on the activity of a virally encoded RNA-dependent polymerase for the condensation of nucleotide triphosphates. This review provides an overview of our current understanding of the viral RNA-dependent polymerase structure and the biochem ...[more]