Ontology highlight
ABSTRACT:
SUBMITTER: Krick T
PROVIDER: S-EPMC4209132 | biostudies-literature | 2014 Nov
REPOSITORIES: biostudies-literature
Krick Teresa T Verstraete Nina N Alonso Leonardo G LG Shub David A DA Ferreiro Diego U DU Shub Michael M Sánchez Ignacio E IE
Molecular biology and evolution 20140801 11
The 20 protein-coding amino acids are found in proteomes with different relative abundances. The most abundant amino acid, leucine, is nearly an order of magnitude more prevalent than the least abundant amino acid, cysteine. Amino acid metabolic costs differ similarly, constraining their incorporation into proteins. On the other hand, a diverse set of protein sequences is necessary to build functional proteomes. Here, we present a simple model for a cost-diversity trade-off postulating that natu ...[more]