Ontology highlight
ABSTRACT:
SUBMITTER: Zhang H
PROVIDER: S-EPMC4209515 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Zhang Husen H Wang Haifeng H Shepherd Megan M Wen Ke K Li Guohua G Yang Xingdong X Kocher Jacob J Giri-Rachman Ernawati E Dickerman Allan A Settlage Robert R Yuan Lijuan L
Gut pathogens 20140909
We generated a neonatal pig model with human infant gut microbiota (HGM) to study the effect of a probiotic on the composition of the transplanted microbiota following rotavirus vaccination and challenge. All the HGM-transplanted pigs received two doses of an oral attenuated rotavirus vaccine. The gut microbiota of vaccinated pigs were investigated for effects of Lactobacillus rhamnosus GG (LGG) supplement and homotypic virulent human rotavirus (HRV) challenge. High-throughput sequencing of V4 r ...[more]