Ontology highlight
ABSTRACT:
SUBMITTER: Li P
PROVIDER: S-EPMC4210162 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Li Pan P Shi Pan P Lai Chaohua C Li Juan J Zheng Yuanyuan Y Xiong Ying Y Zhang Longhua L Tian Changlin C
PloS one 20141027 10
Caenorhabditis elegans MPS1 is a single transmembrane helical auxiliary subunit that co-localizes with the voltage-gated potassium channel KVS1 in the nematode nervous system. MPS-1 shares high homology with KCNE (potassium voltage-gated channel subfamily E member) auxiliary subunits, and its cytosolic domain was reported to have a serine/threonine kinase activity that modulates KVS1 channel function via phosphorylation. In this study, NMR spectroscopy indicated that the full length and truncate ...[more]