Ontology highlight
ABSTRACT:
SUBMITTER: O'Leary OF
PROVIDER: S-EPMC4210293 | biostudies-literature | 2014 Oct
REPOSITORIES: biostudies-literature
O'Leary Olivia F OF Felice Daniela D Galimberti Stefano S Savignac Hélène M HM Bravo Javier A JA Crowley Tadhg T El Yacoubi Malika M Vaugeois Jean-Marie JM Gassmann Martin M Bettler Bernhard B Dinan Timothy G TG Cryan John F JF
Proceedings of the National Academy of Sciences of the United States of America 20141006 42
Stressful life events increase the susceptibility to developing psychiatric disorders such as depression; however, many individuals are resilient to such negative effects of stress. Determining the neurobiology underlying this resilience is instrumental to the development of novel and more effective treatments for stress-related psychiatric disorders. GABAB receptors are emerging therapeutic targets for the treatment of stress-related disorders such as depression. These receptors are predominant ...[more]