Ontology highlight
ABSTRACT:
SUBMITTER: Nam BH
PROVIDER: S-EPMC4210897 | biostudies-literature | 2014 Oct
REPOSITORIES: biostudies-literature
Nam Bo-Hye BH Moon Ji-Young JY Park Eun-Hee EH Kim Young-Ok YO Kim Dong-Gyun DG Kong Hee Jeong HJ Kim Woo-Jin WJ Jee Young Ju YJ An Cheul Min CM Park Nam Gyu NG Seo Jung-Kil JK
Marine drugs 20141017 10
We describe the antimicrobial function of peptides derived from the C-terminus of the olive flounder LBP BPI precursor protein. The investigated peptides, namely, ofLBP1N, ofLBP2A, ofLBP4N, ofLBP5A, and ofLBP6A, formed α-helical structures, showing significant antimicrobial activity against several Gram-negative bacteria, Gram-positive bacteria, and the yeast Candida albicans, but very limited hemolytic activities. The biological activities of these five analogs were evaluated against biomembran ...[more]