Ontology highlight
ABSTRACT:
SUBMITTER: Hoang DT
PROVIDER: S-EPMC4211668 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Hoang Danh-Tai DT Matsunari Hitomi H Nagaya Masaki M Nagashima Hiroshi H Millis J Michael JM Witkowski Piotr P Periwal Vipul V Hara Manami M Jo Junghyo J
PloS one 20141028 10
Morphogenesis, spontaneous formation of organism structure, is essential for life. In the pancreas, endocrine α, β, and δ cells are clustered to form islets of Langerhans, the critical micro-organ for glucose homeostasis. The spatial organization of endocrine cells in islets looks different between species. Based on the three-dimensional positions of individual cells in islets, we computationally inferred the relative attractions between cell types, and found that the attractions between homotyp ...[more]