Ontology highlight
ABSTRACT:
SUBMITTER: Lin S
PROVIDER: S-EPMC4213141 | biostudies-literature | 2014 Nov
REPOSITORIES: biostudies-literature
Lin Suewei S Owald David D Chandra Vikram V Talbot Clifford C Huetteroth Wolf W Waddell Scott S
Nature neuroscience 20140928 11
Drinking water is innately rewarding to thirsty animals. In addition, the consumed value can be assigned to behavioral actions and predictive sensory cues by associative learning. Here we show that thirst converts water avoidance into water-seeking in naive Drosophila melanogaster. Thirst also permitted flies to learn olfactory cues paired with water reward. Water learning required water taste and <40 water-responsive dopaminergic neurons that innervate a restricted zone of the mushroom body γ l ...[more]