Unknown

Dataset Information

0

Bupivacaine Lozenge Compared with Lidocaine Spray as Topical Pharyngeal Anesthetic before Unsedated Upper Gastrointestinal Endoscopy: A Randomized, Controlled Trial.


ABSTRACT: Unsedated upper gastrointestinal endoscopy (UGE) can induce patient discomfort, mainly due to a strong gag reflex. The aim was to assess the effect of a bupivacaine lozenge as topical pharyngeal anesthetic compared with standard treatment with a lidocaine spray before UGE. Ninety-nine adult outpatients undergoing unsedated diagnostic UGE were randomized to receive either a bupivacaine lozenge (L-group, n = 51) or lidocaine spray (S-group, n = 42). Primary objective was assessment of patient discomfort including acceptance of the gag reflex during UGE. The L-group assessed the discomfort significantly lower on a visual analog scale compared with the S-group (P = 0.02). There was also a significant difference in the four-point scale assessment of the gag reflex (P = 0.03). It was evaluated as acceptable by 49% in the L-group compared with 31% in the S-group. A bupivacaine lozenge compared with a lidocaine spray proved to be a superior option as topical pharyngeal anesthetic before an UGE.

SUBMITTER: Salale N 

PROVIDER: S-EPMC4213191 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature

altmetric image

Publications

Bupivacaine Lozenge Compared with Lidocaine Spray as Topical Pharyngeal Anesthetic before Unsedated Upper Gastrointestinal Endoscopy: A Randomized, Controlled Trial.

Salale Nesrin N   Treldal Charlotte C   Mogensen Stine S   Rasmussen Mette M   Petersen Janne J   Andersen Ove O   Jacobsen Jette J  

Clinical medicine insights. Gastroenterology 20141028


Unsedated upper gastrointestinal endoscopy (UGE) can induce patient discomfort, mainly due to a strong gag reflex. The aim was to assess the effect of a bupivacaine lozenge as topical pharyngeal anesthetic compared with standard treatment with a lidocaine spray before UGE. Ninety-nine adult outpatients undergoing unsedated diagnostic UGE were randomized to receive either a bupivacaine lozenge (L-group, n = 51) or lidocaine spray (S-group, n = 42). Primary objective was assessment of patient disc  ...[more]

Similar Datasets

| S-EPMC3417978 | biostudies-literature
| S-EPMC8003238 | biostudies-literature
| S-EPMC5741316 | biostudies-literature
| S-EPMC6793967 | biostudies-literature
| S-EPMC7467465 | biostudies-literature
| S-EPMC10462915 | biostudies-literature
| S-EPMC3891109 | biostudies-literature
| S-EPMC8988023 | biostudies-literature
| S-EPMC1727779 | biostudies-literature
| PRJNA379755 | ENA