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High aerobic intensity training and psychological States in patients with depression or schizophrenia.

ABSTRACT: AIM:To explore changes in psychological states in response to a bout of high aerobic intensity training (HIT) in patients with depression or schizophrenia compared to healthy individuals. METHODS:After familiarization training of HIT, 20 patients with schizophrenia, 13 patients with depression, and 20 healthy individuals performed a no-training day followed by a training day. HIT was 4?×?4?min intervals at 85-95% of peak heart rate, intermitted by 3?min active rest periods at 70% of peak heart rate. Self-evaluation questionnaires of positive affect, negative affect, state anxiety, well-being, distress, and fatigue were completed before training, 15?min after, and 3?h after training. The two latter measures were also completed the no-training day. RESULTS:All three groups improved in positive affect and well-being 15?min after HIT (p??0.05). CONCLUSION:High aerobic intensity training used as an acute intervention improved positive affect and well-being and reduced distress and state anxiety in patients with depression and schizophrenia. ClinicalTrials.gov identifier: NCT01310998.

SUBMITTER: Heggelund J

PROVIDER: S-EPMC4214195 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature

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High aerobic intensity training and psychological States in patients with depression or schizophrenia.

Heggelund Jørn J Kleppe Kim Daniel KD Morken Gunnar G Vedul-Kjelsås Einar E

Frontiers in psychiatry 20141030

<h4>Aim</h4>To explore changes in psychological states in response to a bout of high aerobic intensity training (HIT) in patients with depression or schizophrenia compared to healthy individuals.<h4>Methods</h4>After familiarization training of HIT, 20 patients with schizophrenia, 13 patients with depression, and 20 healthy individuals performed a no-training day followed by a training day. HIT was 4 × 4 min intervals at 85-95% of peak heart rate, intermitted by 3 min active rest periods at 70% ...[more]

PMID: 25400592

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Project description:Previous research combining Calcium ?-hydroxy-?-methylbutyrate (CaHMB) and running high-intensity interval training (HIIT) have shown positive effects on aerobic performance measures. The purpose of this study was to examine the effect of ?-hydroxy-?-methylbutyric free acid (HMBFA) and cycle ergometry HIIT on maximal oxygen consumption (VO2peak), ventilatory threshold (VT), respiratory compensation point (RCP) and time to exhaustion (Tmax) in college-aged men and women.Thirty-four healthy men and women (Age: 22.7?±?3.1 yrs ; VO2peak: 39.3?±?5.0 ml?·?kg(-1)?·?min(-1)) volunteered to participate in this double-blind, placebo-controlled design study. All participants completed a series of tests prior to and following treatment. A peak oxygen consumption test was performed on a cycle ergometer to assess VO2peak, Tmax, VT, and RCP. Twenty-six participants were randomly assigned into either a placebo (PLA-HIIT) or 3 g per day of HMBFA (BetaTor™) (HMBFA-HIIT) group. Eight participants served as controls (CTL). Participants in the HIIT groups completed 12 HIIT (80-120% maximal workload) exercise sessions consisting of 5-6 bouts of a 2:1 minute cycling work to rest ratio protocol over a four-week period. Body composition was measured with dual energy x-ray absorptiometry (DEXA). Outcomes were assessed by ANCOVA with posttest means adjusted for pretest differences.The HMBFA-HIIT intervention showed significant (p?<?0.05) gains in VO2peak, and VT, versus the CTL and PLA-HIIT group. Both PLA-HIIT and HMBFA-HIIT treatment groups demonstrated significant (p?<?0.05) improvement over CTL for Tmax, and RCP with no significant difference between the treatment groups. There were no significant differences observed for any measures of body composition. An independent-samples t-test confirmed that there were no significant differences between the training volumes for the PLA-HIIT and HMBFA-HIIT groups.Our findings support the use of HIIT in combination with HMBFA to improve aerobic fitness in college age men and women. These data suggest that the addition of HMBFA supplementation may result in greater changes in VO2peak and VT than HIIT alone.The study was registered on ClinicalTrials.gov (ID NCT01941368).

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High aerobic intensity training and psychological States in patients with depression or schizophrenia.

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High aerobic intensity training and psychological States in patients with depression or schizophrenia.

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