Ontology highlight
ABSTRACT:
SUBMITTER: Qiu X
PROVIDER: S-EPMC4214273 | biostudies-literature | 2014 Oct
REPOSITORIES: biostudies-literature
Nature 20140829 7520
Without an approved vaccine or treatments, Ebola outbreak management has been limited to palliative care and barrier methods to prevent transmission. These approaches, however, have yet to end the 2014 outbreak of Ebola after its prolonged presence in West Africa. Here we show that a combination of monoclonal antibodies (ZMapp), optimized from two previous antibody cocktails, is able to rescue 100% of rhesus macaques when treatment is initiated up to 5 days post-challenge. High fever, viraemia a ...[more]