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Cassava genome from a wild ancestor to cultivated varieties.


ABSTRACT: Cassava is a major tropical food crop in the Euphorbiaceae family that has high carbohydrate production potential and adaptability to diverse environments. Here we present the draft genome sequences of a wild ancestor and a domesticated variety of cassava and comparative analyses with a partial inbred line. We identify 1,584 and 1,678 gene models specific to the wild and domesticated varieties, respectively, and discover high heterozygosity and millions of single-nucleotide variations. Our analyses reveal that genes involved in photosynthesis, starch accumulation and abiotic stresses have been positively selected, whereas those involved in cell wall biosynthesis and secondary metabolism, including cyanogenic glucoside formation, have been negatively selected in the cultivated varieties, reflecting the result of natural selection and domestication. Differences in microRNA genes and retrotransposon regulation could partly explain an increased carbon flux towards starch accumulation and reduced cyanogenic glucoside accumulation in domesticated cassava. These results may contribute to genetic improvement of cassava through better understanding of its biology.

SUBMITTER: Wang W 

PROVIDER: S-EPMC4214410 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature

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Cassava genome from a wild ancestor to cultivated varieties.

Wang Wenquan W   Feng Binxiao B   Xiao Jingfa J   Xia Zhiqiang Z   Zhou Xincheng X   Li Pinghua P   Zhang Weixiong W   Wang Ying Y   Møller Birger Lindberg BL   Zhang Peng P   Luo Ming-Cheng MC   Xiao Gong G   Liu Jingxing J   Yang Jun J   Chen Songbi S   Rabinowicz Pablo D PD   Chen Xin X   Zhang Hong-Bin HB   Ceballos Henan H   Lou Qunfeng Q   Zou Meiling M   Carvalho Luiz J C B LJ   Zeng Changying C   Xia Jing J   Sun Shixiang S   Fu Yuhua Y   Wang Haiyan H   Lu Cheng C   Ruan Mengbin M   Zhou Shuigeng S   Wu Zhicheng Z   Liu Hui H   Kannangara Rubini Maya RM   Jørgensen Kirsten K   Neale Rebecca Louise RL   Bonde Maya M   Heinz Nanna N   Zhu Wenli W   Wang Shujuan S   Zhang Yang Y   Pan Kun K   Wen Mingfu M   Ma Ping-An PA   Li Zhengxu Z   Hu Meizhen M   Liao Wenbin W   Hu Wenbin W   Zhang Shengkui S   Pei Jinli J   Guo Anping A   Guo Jianchun J   Zhang Jiaming J   Zhang Zhengwen Z   Ye Jianqiu J   Ou Wenjun W   Ma Yaqin Y   Liu Xinyue X   Tallon Luke J LJ   Galens Kevin K   Ott Sandra S   Huang Jie J   Xue Jingjing J   An Feifei F   Yao Qingqun Q   Lu Xiaojing X   Fregene Martin M   López-Lavalle L Augusto Becerra LA   Wu Jiajie J   You Frank M FM   Chen Meili M   Hu Songnian S   Wu Guojiang G   Zhong Silin S   Ling Peng P   Chen Yeyuan Y   Wang Qinghuang Q   Liu Guodao G   Liu Bin B   Li Kaimian K   Peng Ming M  

Nature communications 20141010


Cassava is a major tropical food crop in the Euphorbiaceae family that has high carbohydrate production potential and adaptability to diverse environments. Here we present the draft genome sequences of a wild ancestor and a domesticated variety of cassava and comparative analyses with a partial inbred line. We identify 1,584 and 1,678 gene models specific to the wild and domesticated varieties, respectively, and discover high heterozygosity and millions of single-nucleotide variations. Our analy  ...[more]

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