Ontology highlight
ABSTRACT:
SUBMITTER: Osterman MT
PROVIDER: S-EPMC4214893 | biostudies-literature | 2014 Nov
REPOSITORIES: biostudies-literature
Osterman Mark T MT Aberra Faten N FN Cross Raymond R Liakos Steven S McCabe Robert R Shafran Ira I Wolf Douglas D Hardi Robert R Nessel Lisa L Brensinger Colleen C Gilroy Erin E Lewis James D JD
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20140430 11
<h4>Background & aims</h4>Among patients with quiescent ulcerative colitis (UC), lower fecal concentrations of calprotectin are associated with lower rates of relapse. We performed an open-label, randomized controlled trial to investigate whether increasing doses of mesalamine reduce concentrations of fecal calprotectin (FC) in patients with quiescent UC.<h4>Methods</h4>We screened 119 patients with UC in remission on the basis of Simple Clinical Colitis Activity Index scores, FC >50 μg/g, and i ...[more]