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Displacements of prohead protease genes in the late operons of double-stranded-DNA bacteriophages.


ABSTRACT: Most of the known prohead maturation proteases in double-stranded-DNA bacteriophages are shown, by computational methods, to fall into two evolutionarily independent clans of serine proteases, herpesvirus assemblin-like and ClpP-like. Phylogenetic analysis suggests that these two types of phage prohead protease genes displaced each other multiple times while preserving their exact location within the late operons of the phage genomes.

SUBMITTER: Liu J 

PROVIDER: S-EPMC421614 | biostudies-literature | 2004 Jul

REPOSITORIES: biostudies-literature

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Displacements of prohead protease genes in the late operons of double-stranded-DNA bacteriophages.

Liu Jing J   Mushegian Arcady A  

Journal of bacteriology 20040701 13


Most of the known prohead maturation proteases in double-stranded-DNA bacteriophages are shown, by computational methods, to fall into two evolutionarily independent clans of serine proteases, herpesvirus assemblin-like and ClpP-like. Phylogenetic analysis suggests that these two types of phage prohead protease genes displaced each other multiple times while preserving their exact location within the late operons of the phage genomes. ...[more]

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2024-09-16 | PXD048568 | Pride