Ontology highlight
ABSTRACT:
SUBMITTER: Carlozzi NE
PROVIDER: S-EPMC4217648 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Carlozzi Noelle E NE Miciura Angela A Migliore Nicholas N Dayalu Praveen P
Journal of Huntington's disease 20140101 3
<h4>Background</h4>The identification of the gene mutation causing Huntington disease has raised hopes for new treatments to ease symptoms and slow functional decline. As such, there has been a push towards designing efficient pharmacological trials (i.e., drug trials), especially with regard to selecting outcomes measures that are both brief and sensitive to changes across the course of the disease, from subtle prodromal changes, to more severe end-stage changes.<h4>Objectives</h4>Recently, to ...[more]