Long-term outcomes following development of new-onset atrial fibrillation during sepsis.

ABSTRACT:

Background

New-onset atrial fibrillation (AF) is associated with adverse outcomes during a sepsis hospitalization; however, long-term outcomes following hospitalization with sepsis-associated new-onset AF are unclear.

Methods

We used a Medicare 5% sample to identify patients who survived hospitalization with sepsis between 1999 and 2010. AF status was defined as no AF, prior AF, or new-onset AF based on AF claims during and prior to a sepsis hospitalization. We used competing risk models to determine 5-year risks of AF occurrence, heart failure, ischemic stroke, and mortality after the sepsis hospitalization, according to AF status during the sepsis admission.

Results

We identified 138,722 sepsis survivors, of whom 95,536 (69%) had no AF during sepsis, 33,646 (24%) ha

SUBMITTER: Walkey AJ 

PROVIDER: S-EPMC4219336 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature