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Cryptosporidium cuniculus--new records in human and kangaroo in Australia.

ABSTRACT: To date, Cryptosporidium cuniculus has been found exclusively in rabbits and humans. The present study provides the first published molecular evidence for C. cuniculus in an Australian human patient as well as a kangaroo.Using PCR-based sequencing of regions in the actin, 60 kDa glycoprotein (gp60) and small subunit of ribosomal RNA (SSU) genes, we identified a new and unique C. cuniculus genotype (akin to VbA25) from a human, and C. cuniculus genotype VbA26 from an Eastern grey kangaroo (Macropus giganteus) in Australia.The characterisation of these genotypes raises questions as to their potential to infect humans and/or other animals in Australia, given that C. cuniculus has been reported to cause cryptosporidiosis outbreaks in Europe.

SUBMITTER: Koehler AV

PROVIDER: S-EPMC4221722 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature

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Cryptosporidium cuniculus--new records in human and kangaroo in Australia.

Koehler Anson V AV Whipp Margaret J MJ Haydon Shane R SR Gasser Robin B RB

Parasites & vectors 20141030

<h4>Background</h4>To date, Cryptosporidium cuniculus has been found exclusively in rabbits and humans. The present study provides the first published molecular evidence for C. cuniculus in an Australian human patient as well as a kangaroo.<h4>Findings</h4>Using PCR-based sequencing of regions in the actin, 60 kDa glycoprotein (gp60) and small subunit of ribosomal RNA (SSU) genes, we identified a new and unique C. cuniculus genotype (akin to VbA25) from a human, and C. cuniculus genotype VbA26 f ...[more]

PMID: 25359081

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