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ABSTRACT:
SUBMITTER: Herbrich SM
PROVIDER: S-EPMC4223774 | biostudies-literature | 2013 Feb
REPOSITORIES: biostudies-literature
Herbrich Shelley M SM Cole Robert N RN West Keith P KP Schulze Kerry K Yager James D JD Groopman John D JD Christian Parul P Wu Lee L O'Meally Robert N RN May Damon H DH McIntosh Martin W MW Ruczinski Ingo I
Journal of proteome research 20130116 2
Isobaric tags for relative and absolute quantitation (iTRAQ) is a prominent mass spectrometry technology for protein identification and quantification that is capable of analyzing multiple samples in a single experiment. Frequently, iTRAQ experiments are carried out using an aliquot from a pool of all samples, or "masterpool", in one of the channels as a reference sample standard to estimate protein relative abundances in the biological samples and to combine abundance estimates from multiple ex ...[more]