Ontology highlight
ABSTRACT:
SUBMITTER: Brewoo JN
PROVIDER: S-EPMC4224110 | biostudies-literature | 2013 Apr
REPOSITORIES: biostudies-literature
Brewoo Joseph N JN Powell Tim D TD Jones Jeremy C JC Gundlach Nancy A NA Young Ginger R GR Chu Haiyan H Das Subash C SC Partidos Charalambos D CD Stinchcomb Dan T DT Osorio Jorge E JE
Vaccine 20130201 14
Development of an influenza vaccine that provides cross-protective immunity remains a challenge. Candidate vaccines based on a recombinant modified vaccinia Ankara (MVA) viral vector expressing antigens from influenza (MVA/Flu) viruses were constructed. A vaccine candidate, designated MVA/HA1/C13L/NP, that expresses the hemagglutinin from pandemic H1N1 (A/California/04/09) and the nucleoprotein (NP) from highly pathogenic H5N1 (A/Vietnam/1203/04) fused to a secretory signal sequence from vaccini ...[more]