Ontology highlight
ABSTRACT:
SUBMITTER: Rosic S
PROVIDER: S-EPMC4226727 | biostudies-literature | 2014 Nov
REPOSITORIES: biostudies-literature
Rošić Silvana S Köhler Florian F Erhardt Sylvia S
The Journal of cell biology 20141103 3
Chromosome segregation requires centromeres on every sister chromatid to correctly form and attach the microtubule spindle during cell division. Even though centromeres are essential for genome stability, the underlying centromeric DNA is highly variable in sequence and evolves quickly. Epigenetic mechanisms are therefore thought to regulate centromeres. Here, we show that the 359-bp repeat satellite III (SAT III), which spans megabases on the X chromosome of Drosophila melanogaster, produces a ...[more]