Designer self-assembling hydrogel scaffolds can impact skin cell proliferation and migration.
Ontology highlight
ABSTRACT:
SUBMITTER: Bradshaw M
PROVIDER: S-EPMC4227029 | biostudies-literature | 2014 Nov
REPOSITORIES: biostudies-literature
Publications
Designer self-assembling hydrogel scaffolds can impact skin cell proliferation and migration.
Bradshaw Michael M Ho Diwei D Fear Mark W MW Gelain Fabrizio F Wood Fiona M FM Iyer K Swaminathan KS
Scientific reports 20141111
There is a need to develop economical, efficient and widely available therapeutic approaches to enhance the rate of skin wound healing. The optimal outcome of wound healing is restoration to the pre-wound quality of health. In this study we investigate the cellular response to biological stimuli using functionalized nanofibers from the self-assembling peptide, RADA16. We demonstrate that adding different functional motifs to the RADA16 base peptide can influence the rate of proliferation and mig ...[more]
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