Immunology of psoriasis.
Ontology highlight
ABSTRACT:
SUBMITTER: Lowes MA
PROVIDER: S-EPMC4229247 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Publications
Immunology of psoriasis.
Lowes Michelle A MA Suárez-Fariñas Mayte M Krueger James G JG
Annual review of immunology 20140101
The skin is the front line of defense against insult and injury and contains many epidermal and immune elements that comprise the skin-associated lymphoid tissue (SALT). The reaction of these components to injury allows an effective cutaneous response to restore homeostasis. Psoriasis vulgaris is the best-understood and most accessible human disease that is mediated by T cells and dendritic cells. Inflammatory myeloid dendritic cells release IL-23 and IL-12 to activate IL-17-producing T cells, T ...[more]
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