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ADLD: a novel graphical representation of protein sequences and its application.

ABSTRACT: To facilitate the intuitional analysis of protein sequences, a novel graphical representation of protein sequences called ADLD (Alignment Diagonal Line Diagram) is introduced in this paper first, and then a new ADLD based method is proposed and utilized to analyze the similarity/dissimilarity of protein sequences. Comparing with existing methods, our ADLD based method is proved to be effective in the similarity/dissimilarity analysis of protein sequences and have the merits of good intuition, visuality, and simplicity. The examinations of the similarities/dissimilarities for both the 16 different ND5 proteins and the 29 different spike proteins illustrate the utility of our ADLD based approach.

SUBMITTER: Wang L

PROVIDER: S-EPMC4230005 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature

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ADLD: a novel graphical representation of protein sequences and its application.

Wang Lei L Peng Hui H Zheng Jinhua J

Computational and mathematical methods in medicine 20141030

To facilitate the intuitional analysis of protein sequences, a novel graphical representation of protein sequences called ADLD (Alignment Diagonal Line Diagram) is introduced in this paper first, and then a new ADLD based method is proposed and utilized to analyze the similarity/dissimilarity of protein sequences. Comparing with existing methods, our ADLD based method is proved to be effective in the similarity/dissimilarity analysis of protein sequences and have the merits of good intuition, vi ...[more]

PMID: 25530796

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