Dataset Information

Multiple behavioural impulsivity tasks predict prospective alcohol involvement in adolescents.

ABSTRACT:

Aims

We investigated reciprocal prospective relationships between multiple behavioural impulsivity tasks (assessing delay discounting, risk-taking and disinhibition) and alcohol involvement (consumption, drunkenness and problems) among adolescents. We hypothesized that performance on the tasks would predict subsequent alcohol involvement, and that alcohol involvement would lead to increases in behavioural impulsivity over time.

Design

Cross-lagged prospective design in which impulsivity and alcohol involvement were assessed five times over 2 years (once every 6 months, on average).

Setting

Classrooms in secondary schools in North West England.

Participants

Two hundred and eighty-seven adolescents (51.2% male) who were aged 12 or 13 years at study enrolment.

Measurements

Participants reported their alcohol involvement and completed computerized tasks of disinhibition, delay discounting and risk-taking at each assessment. Cross-sectional and prospective relationships between the variables of interest were investigated using cross-lagged analyses.

Findings

All behavioural impulsivity tasks predicted a composite index of alcohol involvement 6 months later (all Ps?ConclusionsSeveral measures of impulsivity predict escalation in alcohol involvement in young adolescents, but alcohol use does not appear to alter impulsivity.

SUBMITTER: Fernie G

PROVIDER: S-EPMC4230409 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature

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Publications

Multiple behavioural impulsivity tasks predict prospective alcohol involvement in adolescents.

Fernie Gordon G Peeters Margot M Gullo Matthew J MJ Christiansen Paul P Cole Jon C JC Sumnall Harry H Field Matt M

Addiction (Abingdon, England) 20130814 11

<h4>Aims</h4>We investigated reciprocal prospective relationships between multiple behavioural impulsivity tasks (assessing delay discounting, risk-taking and disinhibition) and alcohol involvement (consumption, drunkenness and problems) among adolescents. We hypothesized that performance on the tasks would predict subsequent alcohol involvement, and that alcohol involvement would lead to increases in behavioural impulsivity over time.<h4>Design</h4>Cross-lagged prospective design in which impul ...[more]

PMID: 23795646

Similar Datasets

Project description:BackgroundImpulsivity is genetically correlated with, and precedes, addictive behaviors and alcoholism. If impulsivity or attention is causally related to addiction, certain pharmacological manipulations of impulsivity and/or attention may affect alcohol drinking, and vice versa. The current studies were designed to explore the relationship among impulsivity, drinking, and vigilance in selectively bred High Alcohol Preferring (HAP) mice, a line that has previously demonstrated both high impulsivity and high alcohol consumption. Amphetamine, naltrexone, and memantine were tested in a delay discounting (DD) task for their effects on impulsivity and vigilance. The same drugs and doses were also assessed for effects on alcohol drinking in a 2-bottle choice test.MethodsHAP mice were subjected to a modified version of adjusting amount DD using 0.5-second and 10-second delays to detect decreases and increases, respectively, in impulsive responding. In 2 experiments, mice were given amphetamine (0.4, 0.8, or 1.2 mg/kg), naltrexone (3 and 10 mg/kg), and memantine (1 and 5 mg/kg) before DD testing. Another pair of studies used scheduled access, 2-bottle choice drinking to assess effects of amphetamine (0.4, 1.2, or 3.0 mg/kg), naltrexone (3 and 10 mg/kg), and memantine (1 and 5 mg/kg) on alcohol consumption.ResultsAmphetamine dose-dependently reduced impulsivity and vigilance decrement in DD, but similar doses left alcohol drinking unaffected. Naltrexone and memantine decreased alcohol intake at doses that did not affect water drinking but had no effects on impulsivity or vigilance decrement in the DD task.ConclusionsContrary to our hypothesis, none of the drugs tested here, while effective on either alcohol drinking or impulsivity, decreased both behaviors. These findings suggest that the genetic association between drinking and impulsivity observed in this population is mediated by mechanisms other than those targeted by the drugs tested in these studies.

Dataset Information

Multiple behavioural impulsivity tasks predict prospective alcohol involvement in adolescents.

Aims

Design

Setting

Participants

Measurements

Findings

Publications

Multiple behavioural impulsivity tasks predict prospective alcohol involvement in adolescents.

Similar Datasets

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