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Development of interactive algorithm for clinical management of acute events related to sickle cell disease in emergency department.


ABSTRACT: Sickle cell disease (SCD ORPHA232; OMIM 603903) is a rare hereditary red cell disorder, which global distribution is changed in the last decade due to immigration-fluxes from endemic areas to Western-countries. One of the main clinical manifestations of SCD are the acute painful vaso-occlusive crisis, which cause frequent accesses of SCD patients to the emergency departments (EDs). This has generated the requirement of feasible tools for emergency givers. In the context of the scientific-Italian-Society for the study of Thalassemias and Hemoglobinopathies (SITE), we developed an algorithm with interactive windows to guide physicians in managing SCD patients in EDs.

SUBMITTER: Forni GL 

PROVIDER: S-EPMC4230640 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature

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Development of interactive algorithm for clinical management of acute events related to sickle cell disease in emergency department.

Forni Gian Luca GL   Finco Gabriele G   Graziadei Giovanna G   Balocco Manuela M   Rigano Paolo P   Perrotta Silverio S   Olivieri Oliviero O   Cappellini Maria Domenica MD   De Franceschi Lucia L  

Orphanet journal of rare diseases 20140623


Sickle cell disease (SCD ORPHA232; OMIM 603903) is a rare hereditary red cell disorder, which global distribution is changed in the last decade due to immigration-fluxes from endemic areas to Western-countries. One of the main clinical manifestations of SCD are the acute painful vaso-occlusive crisis, which cause frequent accesses of SCD patients to the emergency departments (EDs). This has generated the requirement of feasible tools for emergency givers. In the context of the scientific-Italian  ...[more]

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