Coffee intake and gastric cancer risk: the Singapore Chinese health study.

ABSTRACT:

Background

Despite experimental evidence showing chemopreventive effects of coffee-related compounds on gastric carcinogenesis, epidemiologic studies generally do not support coffee-gastric cancer associations. Observational data are lacking among high-risk populations with sufficient regular coffee consumption.

Methods

We examined the association between caffeinated coffee intake and gastric cancer risk in a population-based cohort that enrolled 63,257 Chinese men and women ages 45 to 74 years between 1993 and 1998 in Singapore. Incident gastric cancer cases (n = 647) were identified after a mean follow-up of 14.7 years. Biomarkers of Helicobacter pylori (H. pylori) infection were measured in a subset of gastric cancer cases with blood collected before cancer diagnosis and

SUBMITTER: Ainslie-Waldman CE 

PROVIDER: S-EPMC4230822 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature