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Sodium intake in a cross-sectional, representative sample of New York City adults.

ABSTRACT: We estimated sodium intake, which is associated with elevated blood pressure, a major risk factor for cardiovascular disease, and assessed its association with related variables among New York City adults.In 2010 we conducted a cross-sectional, population-based survey of 1656 adults, the Heart Follow-Up Study, that collected self-reported health information, measured blood pressure, and obtained sodium, potassium, and creatinine values from 24-hour urine collections.Mean daily sodium intake was 3239 milligrams per day; 81% of participants exceeded their recommended limit. Sodium intake was higher in non-Hispanic Blacks (3477 mg/d) and Hispanics (3395 mg/d) than in non-Hispanic Whites (3066 mg/d; both P?

SUBMITTER: Angell SY

PROVIDER: S-EPMC4232161 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature

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Sodium intake in a cross-sectional, representative sample of New York City adults.

Angell Sonia Y SY Yi Stella S Eisenhower Donna D Kerker Bonnie D BD Curtis Christine J CJ Bartley Katherine K Silver Lynn D LD Farley Thomas A TA

American journal of public health 20140116 12

<h4>Objectives</h4>We estimated sodium intake, which is associated with elevated blood pressure, a major risk factor for cardiovascular disease, and assessed its association with related variables among New York City adults.<h4>Methods</h4>In 2010 we conducted a cross-sectional, population-based survey of 1656 adults, the Heart Follow-Up Study, that collected self-reported health information, measured blood pressure, and obtained sodium, potassium, and creatinine values from 24-hour urine collec ...[more]

PMID: 24432875

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Project description:ObjectiveTo investigate the effects of lifestyle and vascular-related risk factors for Alzheimer's disease (AD) on in vivo MRI-based brain atrophy in asymptomatic young to middle-aged adults.DesignCross-sectional, observational.SettingBroader New York City area. Two research centres affiliated with the Alzheimer's disease Core Center at New York University School of Medicine.ParticipantsWe studied 116 cognitively normal healthy research participants aged 30-60 years, who completed a three-dimensional T1-weighted volumetric MRI and had lifestyle (diet, physical activity and intellectual enrichment), vascular risk (overweight, hypertension, insulin resistance, elevated cholesterol and homocysteine) and cognition (memory, executive function, language) data. Estimates of cortical thickness for entorhinal (EC), posterior cingulate, orbitofrontal, inferior and middle temporal cortex were obtained by use of automated segmentation tools. We applied confirmatory factor analysis and structural equation modelling to evaluate the associations between lifestyle, vascular risk, brain and cognition.ResultsAdherence to a Mediterranean-style diet (MeDi) and insulin sensitivity were both positively associated with MRI-based cortical thickness (diet: ?s?0.26, insulin sensitivity ?s?0.58, P?0.008). After accounting for vascular risk, EC in turn explained variance in memory (P?0.001). None of the other lifestyle and vascular risk variables were associated with brain thickness. In addition, the path associations between intellectual enrichment and better cognition were significant (?s?0.25 P?0.001), as were those between overweight and lower cognition (?s?-0.22, P?0.01).ConclusionsIn cognitively normal middle-aged adults, MeDi and insulin sensitivity explained cortical thickness in key brain regions for AD, and EC thickness predicted memory performance in turn. Intellectual activity and overweight were associated with cognitive performance through different pathways. Our findings support further investigation of lifestyle and vascular risk factor modification against brain ageing and AD. More studies with larger samples are needed to replicate these research findings in more diverse, community-based settings.

Dataset Information

Sodium intake in a cross-sectional, representative sample of New York City adults.

Publications

Sodium intake in a cross-sectional, representative sample of New York City adults.

Similar Datasets

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