Ontology highlight
ABSTRACT:
SUBMITTER: Etxaniz U
PROVIDER: S-EPMC4235233 | biostudies-literature | 2014 Nov
REPOSITORIES: biostudies-literature
Etxaniz Usue U Pérez-San Vicente Adrián A Gago-López Nuria N García-Dominguez Mario M Iribar Haizea H Aduriz Ariane A Pérez-López Virginia V Burgoa Izaskun I Irizar Haritz H Muñoz-Culla Maider M Vallejo-Illarramendi Ainara A Leis Olatz O Matheu Ander A Martín Angel G AG Otaegui David D López-Mato María Paz MP Gutiérrez-Rivera Araika A MacLellan Robb R Izeta Ander A
Stem cell reports 20141016 5
Resident neural precursor cells (NPCs) have been reported for a number of adult tissues. Understanding their physiological function or, alternatively, their activation after tissue damage or in vitro manipulation remains an unsolved issue. Here, we investigated the source of human dermal NPCs in adult tissue. By following an unbiased, comprehensive approach employing cell-surface marker screening, cell separation, transcriptomic characterization, and in vivo fate analyses, we found that p75NTR(+ ...[more]