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Shining light on the dark side of imaging: excited state absorption enhancement of a bis-styryl BODIPY photoacoustic contrast agent.


ABSTRACT: A first approach toward understanding the targeted design of molecular photoacoustic contrast agents (MPACs) is presented. Optical and photoacoustic Z-scan spectroscopy was used to identify how nonlinear (excited-state) absorption contributes to enhancing the photoacoustic emission of the curcuminBF2 and bis-styryl (MeOPh)2BODIPY dyes relative to Cy3.

SUBMITTER: Frenette M 

PROVIDER: S-EPMC4235371 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature

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Shining light on the dark side of imaging: excited state absorption enhancement of a bis-styryl BODIPY photoacoustic contrast agent.

Frenette Mathieu M   Hatamimoslehabadi Maryam M   Bellinger-Buckley Stephanie S   Laoui Samir S   La Jeffrey J   Bag Seema S   Mallidi Srivalleesha S   Hasan Tayyaba T   Bouma Brett B   Yelleswarapu Chandra C   Rochford Jonathan J  

Journal of the American Chemical Society 20141028 45


A first approach toward understanding the targeted design of molecular photoacoustic contrast agents (MPACs) is presented. Optical and photoacoustic Z-scan spectroscopy was used to identify how nonlinear (excited-state) absorption contributes to enhancing the photoacoustic emission of the curcuminBF2 and bis-styryl (MeOPh)2BODIPY dyes relative to Cy3. ...[more]

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