Ischemia/reperfusion Injury and its Consequences on Immunity and Inflammation.
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ABSTRACT:
SUBMITTER: Slegtenhorst BR
PROVIDER: S-EPMC4235532 | biostudies-literature | 2014 Sep
REPOSITORIES: biostudies-literature
Publications
Ischemia/reperfusion Injury and its Consequences on Immunity and Inflammation.
Slegtenhorst Bendix R BR Dor Frank Jmf FJ Rodriguez Hector H Voskuil Floris J FJ Tullius Stefan G SG
Current transplantation reports 20140901 3
Ischemia/reperfusion injury (IRI), an inherent component of transplantation, affects organ quality and transplant outcomes. Although the complexity of the pathophysiology is recognized, detailed mechanisms remain unclear, and strategies preventing the consequences of IRI have been challenging. Of critical significance appears the link between IRI, the initiation of innate immune responses, and the (potential) augmentation of adaptive immunity. An improved understanding of those complex mechanism ...[more]
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2024-06-01 | GSE254747 | GEO