Metabolomic profiles and childhood obesity.
Ontology highlight
ABSTRACT:
SUBMITTER: Perng W
PROVIDER: S-EPMC4236243 | biostudies-literature | 2014 Dec
REPOSITORIES: biostudies-literature
Publications
Metabolomic profiles and childhood obesity.
Perng Wei W Gillman Matthew W MW Fleisch Abby F AF Michalek Ryan D RD Watkins Steven M SM Isganaitis Elvira E Patti Mary-Elizabeth ME Oken Emily E
Obesity (Silver Spring, Md.) 20140924 12
<h4>Objective</h4>To identify metabolite patterns associated with childhood obesity, to examine relations of these patterns with measures of adiposity and cardiometabolic risk, and to evaluate associations with maternal peripartum characteristics.<h4>Methods</h4>Untargeted metabolomic profiling was used to quantify metabolites in plasma of 262 children (6-10 years). Principal components analysis was used to consolidate 345 metabolites into 18 factors and identified two that differed between obes ...[more]
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